Firecrawl Alexandria
GTEx Portal: gene expression by tissue and eQTLs
The GTEx Portal (Genotype-Tissue Expression project: Broad Institute, NIH Common Fund) through its public API v2, open-access aggregate data only. Median gene expression (TPM) across 54 human tissue sites from about 950 post-mortem donors, and significant single-tissue cis-eQTLs (variant, gene, tissue, normalized effect size, p-value) looked up by gene or by variant (rsID, GTEx variant ID or GRCh38 position). Releases GTEx Analysis v11 (default, GENCODE v47), v10 and v8. Outputs carry Ensembl, GENCODE, NCBI Gene and HGNC gene IDs, dbSNP rsIDs, GRCh38 and GRCh37 variant IDs and UBERON tissue IDs to join with UniProt, Open Targets, HPA, HGNC and NCBI Gene, and the GTEx Portal Data License attribution. No sample-level or donor-level data.
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Codefollows the fields above
const result = await firecrawl.scrape({
alexandria: {
provider: "gtexportal-org",
capability: "expression/tissues",
options: {
gene: "PCSK9",
},
},
});2Response example
This is a sample shape. Press Run to see live data from GTEx Portal: gene expression by tissue and eQTLs.
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{
"dataset": {
"dbgap_accession": null,
"gencode_version": "v47",
"genome_build": "GRCh38/hg38",
"id": "gtex_v11",
"name": "GTEx Analysis v11"
},
"gene": {
"chromosome": "chr1",
"end": 55064852,
"ensembl_gene_id": "ENSG00000169174",
"gencode_id": "ENSG00000169174.13",
"gene_type": "protein coding",
"hgnc_id": "HGNC:20001",
"name": "proprotein convertase subtilisin/kexin type 9",
"ncbi_gene_id": 255738,
"start": 55039445,
"strand": "+",
"symbol": "PCSK9"
},
"license": {
"access": "Open-access aggregate data only: median expression per tissue, significant eQTL summary statistics and reference metadata. No sample-level or donor-level data.",
"attribution": "Data obtained from the GTEx Portal (https://gtexportal.org) on 2026-10-30, GTEx Analysis v11.",
"currency": "Read from the GTEx Portal API at the time of the call, so this is the portal's current data for GTEx Analysis v11; GTEx may have published a newer release since.",
"name": "GTEx Portal Data License",
"no_endorsement": "The GTEx Portal and the GTEx Project have not endorsed Firecrawl or any product, service or application that uses this data.",
"url": "https://gtexportal.org/home/license"
},
"observed_at_ms": 1793395786146,
"query": "PCSK9",
"source_url": "https://gtexportal.org/home/gene/PCSK9",
"tissues": [
{
"median_tpm": 26.467,
"rank": 1,
"rna_seq_samples": 261,
"tissue_id": "Liver",
"tissue_name": "Liver",
"tissue_ontology_id": "UBERON:0001114",
"tissue_site": "Liver"
},
{
"median_tpm": 21.256,
"rank": 2,
"rna_seq_samples": 276,
"tissue_id": "Brain_Cerebellar_Hemisphere",
"tissue_name": "Brain - Cerebellar Hemisphere",
"tissue_ontology_id": "UBERON:0002037",
"tissue_site": "Brain"
},
{
"median_tpm": 20.2374,
"rank": 3,
"rna_seq_samples": 264,
"tissue_id": "Brain_Cerebellum",
"tissue_name": "Brain - Cerebellum",
"tissue_ontology_id": "UBERON:0002037",
"tissue_site": "Brain"
},
{
"median_tpm": 7.06649,
"rank": 4,
"rna_seq_samples": 601,
"tissue_id": "Lung",
"tissue_name": "Lung",
"tissue_ontology_id": "UBERON:0008952",
"tissue_site": "Lung"
},
{
"median_tpm": 5.31771,
"rank": 5,
"rna_seq_samples": 614,
"tissue_id": "Esophagus_Mucosa",
"tissue_name": "Esophagus - Mucosa",
"tissue_ontology_id": "UBERON:0006920",
"tissue_site": "Esophagus"
},
{
"median_tpm": 2.98475,
"rank": 6,
"rna_seq_samples": 206,
"tissue_id": "Small_Intestine_Terminal_Ileum",
"tissue_name": "Small Intestine - Terminal Ileum",
"tissue_ontology_id": "UBERON:0001211",
"tissue_site": "Small Intestine"
},
{
"median_tpm": 2.78089,
"rank": 7,
"rna_seq_samples": 362,
"tissue_id": "Pancreas",
"tissue_name": "Pancreas",
"tissue_ontology_id": "UBERON:0001150",
"tissue_site": "Pancreas"
},
{
"median_tpm": 1.96578,
"rank": 8,
"rna_seq_samples": 667,
"tissue_id": "Nerve_Tibial",
"tissue_name": "Nerve - Tibial",
"tissue_ontology_id": "UBERON:0001323",
"tissue_site": "Nerve"
},
{
"median_tpm": 1.74532,
"rank": 9,
"rna_seq_samples": 478,
"tissue_id": "Colon_Transverse",
"tissue_name": "Colon - Transverse",
"tissue_ontology_id": "UBERON:0001157",
"tissue_site": "Colon"
},
{
"median_tpm": 1.6321,
"rank": 10,
"rna_seq_samples": 751,
"tissue_id": "Skin_Sun_Exposed_Lower_leg",
"tissue_name": "Skin - Sun Exposed (Lower leg)",
"tissue_ontology_id": "UBERON:8480050",
"tissue_site": "Skin"
},
{
"median_tpm": 1.27059,
"rank": 11,
"rna_seq_samples": 170,
"tissue_id": "Vagina",
"tissue_name": "Vagina",
"tissue_ontology_id": "UBERON:0000996",
"tissue_site": "Vagina"
},
{
"median_tpm": 1.23561,
"rank": 12,
"rna_seq_samples": 649,
"tissue_id": "Skin_Not_Sun_Exposed_Suprapubic",
"tissue_name": "Skin - Not Sun Exposed (Suprapubic)",
"tissue_ontology_id": "UBERON:0036149",
"tissue_site": "Skin"
},
{
"median_tpm": 1.15509,
"rank": 13,
"rna_seq_samples": 413,
"tissue_id": "Testis",
"tissue_name": "Testis",
"tissue_ontology_id": "UBERON:0000473",
"tissue_site": "Testis"
},
{
"median_tpm": 0.816652,
"rank": 14,
"rna_seq_samples": null,
"tissue_id": "Cervix_Ectocervix",
"tissue_name": "Cervix - Ectocervix",
"tissue_ontology_id": "UBERON:0012249",
"tissue_site": "Cervix Uteri"
},
{
"median_tpm": 0.516851,
"rank": 15,
"rna_seq_samples": 649,
"tissue_id": "Cells_Cultured_fibroblasts",
"tissue_name": "Cells - Cultured fibroblasts",
"tissue_ontology_id": "EFO:0002009",
"tissue_site": "Skin"
},
{
"median_tpm": 0.37432,
"rank": 16,
"rna_seq_samples": 800,
"tissue_id": "Whole_Blood",
"tissue_name": "Whole Blood",
"tissue_ontology_id": "UBERON:0013756",
"tissue_site": "Blood"
},
{
"median_tpm": 0.347208,
"rank": 17,
"rna_seq_samples": 407,
"tissue_id": "Stomach",
"tissue_name": "Stomach",
"tissue_ontology_id": "UBERON:0000945",
"tissue_site": "Stomach"
},
{
"median_tpm": 0.317282,
"rank": 18,
"rna_seq_samples": null,
"tissue_id": "Kidney_Medulla",
"tissue_name": "Kidney - Medulla",
"tissue_ontology_id": "UBERON:0001293",
"tissue_site": "Kidney"
},
{
"median_tpm": 0.282928,
"rank": 19,
"rna_seq_samples": 584,
"tissue_id": "Adipose_Visceral_Omentum",
"tissue_name": "Adipose - Visceral (Omentum)",
"tissue_ontology_id": "UBERON:0010414",
"tissue_site": "Adipose Tissue"
},
{
"median_tpm": 0.257333,
"rank": 20,
"rna_seq_samples": 277,
"tissue_id": "Spleen",
"tissue_name": "Spleen",
"tissue_ontology_id": "UBERON:0002106",
"tissue_site": "Spleen"
},
{
"median_tpm": 0.232392,
"rank": 21,
"rna_seq_samples": null,
"tissue_id": "Cervix_Endocervix",
"tissue_name": "Cervix - Endocervix",
"tissue_ontology_id": "UBERON:0000458",
"tissue_site": "Cervix Uteri"
},
{
"median_tpm": 0.218174,
"rank": 22,
"rna_seq_samples": 284,
"tissue_id": "Brain_Nucleus_accumbens_basal_ganglia",
"tissue_name": "Brain - Nucleus accumbens (basal ganglia)",
"tissue_ontology_id": "UBERON:0001882",
"tissue_site": "Brain"
},
{
"median_tpm": 0.218172,
"rank": 23,
"rna_seq_samples": null,
"tissue_id": "Fallopian_Tube",
"tissue_name": "Fallopian Tube",
"tissue_ontology_id": "UBERON:0003889",
"tissue_site": "Fallopian Tube"
},
{
"median_tpm": 0.205447,
"rank": 24,
"rna_seq_samples": 472,
"tissue_id": "Artery_Aorta",
"tissue_name": "Artery - Aorta",
"tissue_ontology_id": "UBERON:0001496",
"tissue_site": "Blood Vessel"
},
{
"median_tpm": 0.160712,
"rank": 25,
"rna_seq_samples": 561,
"tissue_id": "Esophagus_Muscularis",
"tissue_name": "Esophagus - Muscularis",
"tissue_ontology_id": "UBERON:0004648",
"tissue_site": "Esophagus"
},
{
"median_tpm": 0.148748,
"rank": 26,
"rna_seq_samples": 295,
"tissue_id": "Adrenal_Gland",
"tissue_name": "Adrenal Gland",
"tissue_ontology_id": "UBERON:0002369",
"tissue_site": "Adrenal Gland"
},
{
"median_tpm": 0.143178,
"rank": 27,
"rna_seq_samples": 103,
"tissue_id": "Kidney_Cortex",
"tissue_name": "Kidney - Cortex",
"tissue_ontology_id": "UBERON:0001225",
"tissue_site": "Kidney"
},
{
"median_tpm": 0.136564,
"rank": 28,
"rna_seq_samples": 403,
"tissue_id": "Esophagus_Gastroesophageal_Junction",
"tissue_name": "Esophagus - Gastroesophageal Junction",
"tissue_ontology_id": "UBERON:0004550",
"tissue_site": "Esophagus"
},
{
"median_tpm": 0.127694,
"rank": 29,
"rna_seq_samples": 268,
"tissue_id": "Brain_Cortex",
"tissue_name": "Brain - Cortex",
"tissue_ontology_id": "UBERON:0001870",
"tissue_site": "Brain"
},
{
"median_tpm": 0.125689,
"rank": 30,
"rna_seq_samples": 203,
"tissue_id": "Brain_Spinal_cord_cervical_c-1",
"tissue_name": "Brain - Spinal cord (cervical c-1)",
"tissue_ontology_id": "UBERON:0006469",
"tissue_site": "Brain"
},
{
"median_tpm": 0.122455,
"rank": 31,
"rna_seq_samples": 256,
"tissue_id": "Brain_Hypothalamus",
"tissue_name": "Brain - Hypothalamus",
"tissue_ontology_id": "UBERON:0001898",
"tissue_site": "Brain"
},
{
"median_tpm": 0.122413,
"rank": 32,
"rna_seq_samples": 77,
"tissue_id": "Bladder",
"tissue_name": "Bladder",
"tissue_ontology_id": "UBERON:0001255",
"tissue_site": "Bladder"
},
{
"median_tpm": 0.117542,
"rank": 33,
"rna_seq_samples": 268,
"tissue_id": "Brain_Frontal_Cortex_BA9",
"tissue_name": "Brain - Frontal Cortex (BA9)",
"tissue_ontology_id": "UBERON:0009834",
"tissue_site": "Brain"
},
{
"median_tpm": 0.108508,
"rank": 34,
"rna_seq_samples": 689,
"tissue_id": "Artery_Tibial",
"tissue_name": "Artery - Tibial",
"tissue_ontology_id": "UBERON:0007610",
"tissue_site": "Blood Vessel"
},
{
"median_tpm": 0.108214,
"rank": 35,
"rna_seq_samples": 180,
"tissue_id": "Minor_Salivary_Gland",
"tissue_name": "Minor Salivary Gland",
"tissue_ontology_id": "UBERON:0006330",
"tissue_site": "Salivary Gland"
},
{
"median_tpm": 0.103932,
"rank": 36,
"rna_seq_samples": 511,
"tissue_id": "Breast_Mammary_Tissue",
"tissue_name": "Breast - Mammary Tissue",
"tissue_ontology_id": "UBERON:0008367",
"tissue_site": "Breast"
},
{
"median_tpm": 0.102655,
"rank": 37,
"rna_seq_samples": 281,
"tissue_id": "Prostate",
"tissue_name": "Prostate",
"tissue_ontology_id": "UBERON:0002367",
"tissue_site": "Prostate"
},
{
"median_tpm": 0.096918,
"rank": 38,
"rna_seq_samples": 311,
"tissue_id": "Pituitary",
"tissue_name": "Pituitary",
"tissue_ontology_id": "UBERON:0000007",
"tissue_site": "Pituitary"
},
{
"median_tpm": 0.08593,
"rank": 39,
"rna_seq_samples": 268,
"tissue_id": "Artery_Coronary",
"tissue_name": "Artery - Coronary",
"tissue_ontology_id": "UBERON:0001621",
"tissue_site": "Blood Vessel"
},
{
"median_tpm": 0.075287,
"rank": 40,
"rna_seq_samples": 418,
"tissue_id": "Colon_Sigmoid",
"tissue_name": "Colon - Sigmoid",
"tissue_ontology_id": "UBERON:0001159",
"tissue_site": "Colon"
},
{
"median_tpm": 0.075269,
"rank": 41,
"rna_seq_samples": 152,
"tissue_id": "Uterus",
"tissue_name": "Uterus",
"tissue_ontology_id": "UBERON:0000995",
"tissue_site": "Uterus"
},
{
"median_tpm": 0.0747005,
"rank": 42,
"rna_seq_samples": 711,
"tissue_id": "Adipose_Subcutaneous",
"tissue_name": "Adipose - Subcutaneous",
"tissue_ontology_id": "UBERON:0002190",
"tissue_site": "Adipose Tissue"
},
{
"median_tpm": 0.073151,
"rank": 43,
"rna_seq_samples": 192,
"tissue_id": "Ovary",
"tissue_name": "Ovary",
"tissue_ontology_id": "UBERON:0000992",
"tissue_site": "Ovary"
},
{
"median_tpm": 0.06446,
"rank": 44,
"rna_seq_samples": 233,
"tissue_id": "Brain_Anterior_cingulate_cortex_BA24",
"tissue_name": "Brain - Anterior cingulate cortex (BA24)",
"tissue_ontology_id": "UBERON:0009835",
"tissue_site": "Brain"
},
{
"median_tpm": 0.055029,
"rank": 45,
"rna_seq_samples": 183,
"tissue_id": "Brain_Substantia_nigra",
"tissue_name": "Brain - Substantia nigra",
"tissue_ontology_id": "UBERON:0002038",
"tissue_site": "Brain"
},
{
"median_tpm": 0.040236,
"rank": 46,
"rna_seq_samples": 254,
"tissue_id": "Brain_Hippocampus",
"tissue_name": "Brain - Hippocampus",
"tissue_ontology_id": "UBERON:0001954",
"tissue_site": "Brain"
},
{
"median_tpm": 0.035153,
"rank": 47,
"rna_seq_samples": 180,
"tissue_id": "Brain_Amygdala",
"tissue_name": "Brain - Amygdala",
"tissue_ontology_id": "UBERON:0001876",
"tissue_site": "Brain"
},
{
"median_tpm": 0.0302535,
"rank": 48,
"rna_seq_samples": 681,
"tissue_id": "Thyroid",
"tissue_name": "Thyroid",
"tissue_ontology_id": "UBERON:0002046",
"tissue_site": "Thyroid"
},
{
"median_tpm": 0.02437,
"rank": 49,
"rna_seq_samples": 460,
"tissue_id": "Heart_Atrial_Appendage",
"tissue_name": "Heart - Atrial Appendage",
"tissue_ontology_id": "UBERON:0006631",
"tissue_site": "Heart"
},
{
"median_tpm": 0.0227135,
"rank": 50,
"rna_seq_samples": 298,
"tissue_id": "Brain_Caudate_basal_ganglia",
"tissue_name": "Brain - Caudate (basal ganglia)",
"tissue_ontology_id": "UBERON:0001873",
"tissue_site": "Brain"
},
"… [4 more items]"
],
"tissues_filter": [],
"total_tissues": 54,
"unit": "TPM"
}Data obtained from the GTEx Portal on the date shown in each result (GTEx Analysis v11, open-access aggregates only). The GTEx Portal and the GTEx Project have not endorsed Firecrawl or any product using this data, and GTEx may have published newer data since. (https://gtexportal.org/home/license)
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