Firecrawl Alexandria

HGNC (HUGO Gene Nomenclature Committee)

HGNC, the authority for human gene names, through the genenames.org REST API: resolve any gene symbol, alias, previous symbol or ID (HGNC, NCBI Gene, Ensembl, UniProt, RefSeq, MGI, RGD) to the current approved symbol, with ambiguous aliases listed rather than guessed; check up to 50 genes at once; and search genes by name, symbol pattern, cytoband or locus type. Records carry the approved name, aliases, previous symbols, locus type, location, gene groups and cross-references that join NCBI Gene, Ensembl, UniProt, OMIM and PubMed. HGNC data is CC0.

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What is the approved HGNC symbol for the gene papers call HER2, and what are its NCBI Gene, Ensembl and UniProt IDs?

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const result = await firecrawl.scrape({
  alexandria: {
    provider: "genenames-org",
    capability: "genes/get",
    options: {
      gene: "p53",
    },
  },
});

2Response example

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{
  "candidates": [],
  "gene": {
    "alias_names": [
      "Li-Fraumeni syndrome"
    ],
    "alias_symbols": [
      "p53",
      "LFS1"
    ],
    "cross_references": {
      "ccds_ids": [
        "CCDS11118",
        "CCDS45605",
        "CCDS45606",
        "CCDS73963",
        "CCDS73964",
        "CCDS73965",
        "CCDS73966",
        "CCDS73967",
        "CCDS73968",
        "CCDS73969",
        "CCDS73970",
        "CCDS73971"
      ],
      "ensembl_gene_id": "ENSG00000141510",
      "enzyme_ids": [],
      "mane_select": {
        "ensembl_transcript": "ENST00000269305.9",
        "refseq_transcript": "NM_000546.6"
      },
      "mgi_ids": [
        "MGI:98834"
      ],
      "mirbase_id": null,
      "ncbi_gene_id": "7157",
      "omim_ids": [
        "191170"
      ],
      "orphanet_id": "120204",
      "pubmed_ids": [
        "6396087",
        "3456488",
        "2047879"
      ],
      "refseq_accessions": [
        "NM_000546"
      ],
      "rgd_ids": [
        "RGD:3889"
      ],
      "rnacentral_ids": [],
      "uniprot_ids": [
        "P04637"
      ]
    },
    "curator_notes": [],
    "date_approved": "1986-01-01",
    "date_modified": "2023-01-20",
    "date_name_changed": "2008-01-16",
    "date_symbol_changed": null,
    "gene_groups": [
      {
        "id": 4068,
        "name": "p53 transcription factor family",
        "url": "https://www.genenames.org/data/genegroup/#!/group/4068"
      }
    ],
    "hgnc_id": "HGNC:11998",
    "location": "17p13.1",
    "locus_group": "protein-coding gene",
    "locus_type": "gene with protein product",
    "name": "tumor protein p53",
    "previous_names": [],
    "previous_symbols": [],
    "source_url": "https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:11998",
    "status": "approved",
    "symbol": "TP53"
  },
  "input": "p53",
  "license": {
    "attribution": "HGNC Database, HUGO Gene Nomenclature Committee (HGNC), www.genenames.org (RRID:SCR_002827). Cite: Seal RL et al., Genenames.org: the HGNC resources in 2023, Nucleic Acids Res. 2023. CC0: attribution is recommended, not required.",
    "name": "CC0 1.0",
    "url": "https://creativecommons.org/publicdomain/zero/1.0/"
  },
  "matched_on": "alias_symbol",
  "note": "p53 is an alias of TP53 (HGNC:11998); the approved symbol is TP53.",
  "observed_at_ms": 1792529111647,
  "resolution": "resolved"
}

HGNC (HUGO Gene Nomenclature Committee)

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