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ISRCTN

ISRCTN, the UK's primary clinical study registry and a WHO primary registry (run by BioMed Central, part of Springer Nature), through its public XML API: search about 29,000 interventional and observational studies by condition, intervention, sponsor, funder, title, recruitment country, phase, registration date or computed recruitment status, and read one full record by ISRCTN, URL or a linked NCT, EudraCT, CTIS, IRAS or CPMS number, with eligibility, outcomes, centres, sponsors, funders, secondary identifiers and linked publications (PMIDs, DOIs). Records are CC BY 4.0: every result carries its licence, the study DOI and a citation.

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Which UK asthma studies on ISRCTN are recruiting right now?

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ISRCTN
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1Request
string

Condition or disease, matched as a phrase, e.g. "breast cancer".

string

Recruitment country as the registry names it ("United Kingdom", "United States of America", "Korea, South"); UK, US, USA and common aliases work. "United Kingdom" also matches studies that list only England, Scotland, Wales or Northern Ireland.

string

Funder name, matched as a phrase, e.g. "Wellcome Trust".

number

Studies per page.

5 credits
Codefollows the fields above
const result = await firecrawl.scrape({
  alexandria: {
    provider: "isrctn-com",
    capability: "clinical-trials/search",
    options: {
      condition: "asthma",
      country: "United Kingdom",
      page_size: 3,
    },
  },
});
2Response example

This is a sample shape. Press Run to see live data from ISRCTN.

{
  "api_url": "https://www.isrctn.com/api/query/format/default?q=condition%3A%22asthma%22%20AND%20%28recruitmentCountry%3A%22United%20Kingdom%22%20OR%20recruitmentCountry%3A%22England%22%20OR%20recruitmentCountry%3A%22Scotland%22%20OR%20recruitmentCountry%3A%22Wales%22%20OR%20recruitmentCountry%3A%22Northern%20Ireland%22%29&limit=3",
  "license": {
    "attribution": "Study records from the ISRCTN registry (https://www.isrctn.com), contributed by each study's registering researchers under CC BY 4.0; cite a study by its DOI.",
    "name": "CC BY 4.0",
    "url": "https://creativecommons.org/licenses/by/4.0/"
  },
  "next_page_token": "20260827072933741657_1_a679746c",
  "observed_at_ms": 1792531058355,
  "query": "condition:\"asthma\" AND (recruitmentCountry:\"United Kingdom\" OR recruitmentCountry:\"England\" OR recruitmentCountry:\"Scotland\" OR recruitmentCountry:\"Wales\" OR recruitmentCountry:\"Northern Ireland\")",
  "studies": [
    {
      "acronym": "WRAPT",
      "brief_title": "Weight reduction in asthma programme with tirzepatide",
      "completion_date": "2028-01-01",
      "conditions": [
        "Asthma with obesity"
      ],
      "countries": [
        "United Kingdom",
        "England"
      ],
      "doi": "10.1186/ISRCTN91904759",
      "enrollment": {
        "count": 138,
        "type": "ESTIMATED"
      },
      "has_results": false,
      "interventions": [
        {
          "name": "Tirzepatide",
          "type": "Drug"
        }
      ],
      "isrctn": "ISRCTN91904759",
      "last_updated_date": "2026-10-09",
      "lead_sponsor": {
        "class": null,
        "name": "University of East Anglia"
      },
      "nct_ids": [],
      "official_title": "Weight Reduction in Asthma Programme with Tirzepatide (WRAPT): clinical efficacy and mechanisms of action",
      "overall_status": "ONGOING",
      "phases": [
        "PHASE2"
      ],
      "recruitment_end_date": "2027-10-31",
      "recruitment_start_date": "2026-11-09",
      "recruitment_status": "NOT_YET_RECRUITING",
      "registered_date": "2026-09-21",
      "source_url": "https://www.isrctn.com/ISRCTN91904759",
      "study_type": "INTERVENTIONAL",
      "why_stopped": null
    },
    {
      "acronym": "CSAREA",
      "brief_title": "Study of the effect of non-adherence to standard asthma preventer treatment (inhaled steroids) on response to biologic treatment (mepolizumab) in people with severe asthma",
      "completion_date": "2024-08-31",
      "conditions": [
        "Severe eosinophilic asthma"
      ],
      "countries": [
        "United Kingdom",
        "England"
      ],
      "doi": "10.1186/ISRCTN10555748",
      "enrollment": {
        "count": 201,
        "type": "ACTUAL"
      },
      "has_results": false,
      "interventions": [
        {
          "name": "Mepolizumab",
          "type": "Biological/Vaccine"
        }
      ],
      "isrctn": "ISRCTN10555748",
      "last_updated_date": "2026-09-02",
      "lead_sponsor": {
        "class": null,
        "name": "University Hospitals Birmingham NHS Foundation Trust"
      },
      "nct_ids": [],
      "official_title": "Non-adherence to inhaled corticosteroids is associated with negative mepolizumab response",
      "overall_status": "COMPLETED",
      "phases": [],
      "recruitment_end_date": "2024-08-31",
      "recruitment_start_date": "2022-05-03",
      "recruitment_status": "NO_LONGER_RECRUITING",
      "registered_date": "2026-09-02",
      "source_url": "https://www.isrctn.com/ISRCTN10555748",
      "study_type": "OBSERVATIONAL",
      "why_stopped": null
    },
    {
      "acronym": "FLU2025-DMF-CFD-v1",
      "brief_title": "A study to develop a computer model for measuring how a drug is distributed in the lungs",
      "completion_date": "2026-09-25",
      "conditions": [
        "Chronic obstructive pulmonary disease (COPD), asthma"
      ],
      "countries": [
        "United Kingdom",
        "Wales",
        "Belgium"
      ],
      "doi": "10.1186/ISRCTN86996855",
      "enrollment": {
        "count": 15,
        "type": "ESTIMATED"
      },
      "has_results": false,
      "interventions": [
        {
          "name": "Ipratropium bromide (monohydrate),  fluticasone propionate,  glycopyrrolate, formoterol fumarate dihydrate",
          "type": "Drug"
        }
      ],
      "isrctn": "ISRCTN86996855",
      "last_updated_date": "2026-08-27",
      "lead_sponsor": {
        "class": null,
        "name": "Fluidda (Belgium)"
      },
      "nct_ids": [],
      "official_title": "A prospective study to support validation of computational fluid dynamics based lung deposition models with nuclear medicine imaging methods",
      "overall_status": "COMPLETED",
      "phases": [
        "PHASE1"
      ],
      "recruitment_end_date": "2026-09-14",
      "recruitment_start_date": "2026-06-30",
      "recruitment_status": "NO_LONGER_RECRUITING",
      "registered_date": "2026-08-27",
      "source_url": "https://www.isrctn.com/ISRCTN86996855",
      "study_type": "INTERVENTIONAL",
      "why_stopped": null
    }
  ],
  "total_count": 177
}

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