Firecrawl Alexandria

ChEMBL

ChEMBL, EMBL-EBI's open database of bioactive drug-like molecules (www.ebi.ac.uk/chembl), through its keyless JSON web services: molecule search by name or synonym and molecule records (structure, properties, max phase, synonyms, mechanisms of action), drug indications with EFO/MeSH terms and phases, drug targets with UniProt accessions, and bioactivity measurements (IC50, Ki, Kd, EC50, pChEMBL) by molecule and/or target. Data CC BY-SA 3.0 (attribution, share-alike); every output carries the licence and ChEMBL release.

Try in Agent

What is imatinib's mechanism of action and what is it approved for, according to ChEMBL?

Try ChEMBL now.

Choose an example or ask your own question.

What do you want to do with ChEMBL?

TRY ASKING

Codefollows the fields above

const result = await firecrawl.scrape({
  alexandria: {
    provider: "ebi-ac-uk",
    capability: "molecules/drug_indications",
    options: {
      chembl_id: "CHEMBL941",
      limit: 5,
    },
  },
});

2Response example

This is a sample shape. Press Run to see live data from ChEMBL.

{
  "attribution": {
    "citation": "Zdrazil B, et al. The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res. 2024;52(D1):D1180-D1192. doi:10.1093/nar/gkad1004",
    "license": "CC BY-SA 3.0",
    "license_url": "https://creativecommons.org/licenses/by-sa/3.0/",
    "release": "ChEMBL_37",
    "release_date": "2026-05-01",
    "source": "ChEMBL, EMBL-EBI",
    "source_url": "https://www.ebi.ac.uk/chembl/",
    "terms_url": "https://www.ebi.ac.uk/about/terms-of-use",
    "text": "Data from ChEMBL (ChEMBL_37), EMBL-EBI, https://www.ebi.ac.uk/chembl/, licensed under CC BY-SA 3.0 (https://creativecommons.org/licenses/by-sa/3.0/). Keep ChEMBL IDs and the release number when you reuse it; adaptations you distribute must carry the same licence."
  },
  "indications": [
    {
      "drugind_id": 23307,
      "efo_id": "EFO:0000339",
      "efo_term": "chronic myelogenous leukemia",
      "license": "CC BY-SA 3.0",
      "max_phase_for_ind": 4,
      "mesh_heading": "Leukemia, Myelogenous, Chronic, BCR-ABL Positive",
      "mesh_id": "D015464",
      "molecule_chembl_id": "CHEMBL1642",
      "parent_molecule_chembl_id": "CHEMBL941",
      "references": [
        {
          "id": "NCT00015834,NCT00030394,NCT00038649,NCT00040105,NCT00047502,NCT00048672,NCT00049192,NCT00050531,NCT00054431,NCT00070499,NCT00081926,NCT00088231,NCT00101088,NCT00114959,NCT00124748,NCT00146913,NCT00171158,NCT00171223,NCT00171899,NCT00210119,NCT00219726,NCT00219739,NCT00219752,NCT00219765,NCT00390897,NCT00415909,NCT00511303,NCT00514488,NCT00594555,NCT00702403,NCT00845221,NCT01003054,NCT01221376,NCT01400074,NCT01578213,NCT01795716,NCT01827930,NCT02204644,NCT02687425,NCT02709083,NCT03241199,NCT04626024,NCT05623774",
          "type": "ClinicalTrials",
          "url": "https://clinicaltrials.gov/search?term=NCT00015834%20NCT00030394%20NCT00038649%20NCT00040105%20NCT00047502%20NCT00048672%20NCT00049192%20NCT00050531%20NCT00054431%20NCT00070499%20NCT00081926%20NCT00088231%20NCT00101088%20NCT00114959%20NCT00124748%20NCT00146913%20NCT00171158%20NCT00171223%20NCT00171899%20NCT00210119%20NCT00219726%20NCT00219739%20NCT00219752%20NCT00219765%20NCT00390897%20NCT00415909%20NCT00511303%20NCT00514488%20NCT00594555%20NCT00702403%20NCT00845221%20NCT01003054%20NCT01221376%20NCT01400074%20NCT01578213%20NCT01795716%20NCT01827930%20NCT02204644%20NCT02687425%20NCT02709083%20NCT03241199%20NCT04626024%20NCT05623774"
        },
        {
          "id": "0e9927ab-771e-4c2d-881e-7031c40bf205",
          "type": "DailyMed",
          "url": "https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=0e9927ab-771e-4c2d-881e-7031c40bf205"
        },
        {
          "id": "211ef2da-2868-4a77-8055-1cb2cd78e24b",
          "type": "DailyMed",
          "url": "https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=211ef2da-2868-4a77-8055-1cb2cd78e24b"
        }
      ],
      "source_url": "https://www.ebi.ac.uk/chembl/api/data/drug_indication/23307.json"
    },
    {
      "drugind_id": 24517,
      "efo_id": "EFO:0000220",
      "efo_term": "acute lymphoblastic leukemia",
      "license": "CC BY-SA 3.0",
      "max_phase_for_ind": 4,
      "mesh_heading": "Precursor Cell Lymphoblastic Leukemia-Lymphoma",
      "mesh_id": "D054198",
      "molecule_chembl_id": "CHEMBL1642",
      "parent_molecule_chembl_id": "CHEMBL941",
      "references": [
        {
          "id": "NCT00154349,NCT00388895,NCT01222013,NCT01312818,NCT03023046",
          "type": "ClinicalTrials",
          "url": "https://clinicaltrials.gov/search?term=NCT00154349%20NCT00388895%20NCT01222013%20NCT01312818%20NCT03023046"
        }
      ],
      "source_url": "https://www.ebi.ac.uk/chembl/api/data/drug_indication/24517.json"
    },
    {
      "drugind_id": 52060,
      "efo_id": "EFO:1001467",
      "efo_term": "Hypereosinophilic syndrome",
      "license": "CC BY-SA 3.0",
      "max_phase_for_ind": 4,
      "mesh_heading": "Hypereosinophilic Syndrome",
      "mesh_id": "D017681",
      "molecule_chembl_id": "CHEMBL1642",
      "parent_molecule_chembl_id": "CHEMBL941",
      "references": [
        {
          "id": "NCT00171860,NCT00230334",
          "type": "ClinicalTrials",
          "url": "https://clinicaltrials.gov/search?term=NCT00171860%20NCT00230334"
        },
        {
          "id": "EMEA/H/C/000406",
          "type": "EMA",
          "url": "https://www.ema.europa.eu/en/medicines/human/EPAR/glivec"
        }
      ],
      "source_url": "https://www.ebi.ac.uk/chembl/api/data/drug_indication/52060.json"
    },
    {
      "drugind_id": 117423,
      "efo_id": "MONDO:0000870",
      "efo_term": "childhood acute lymphoblastic leukemia",
      "license": "CC BY-SA 3.0",
      "max_phase_for_ind": 4,
      "mesh_heading": "Precursor Cell Lymphoblastic Leukemia-Lymphoma",
      "mesh_id": "D054198",
      "molecule_chembl_id": "CHEMBL1642",
      "parent_molecule_chembl_id": "CHEMBL941",
      "references": [
        {
          "id": "NCT00022737,NCT00702403",
          "type": "ClinicalTrials",
          "url": "https://clinicaltrials.gov/search?term=NCT00022737%20NCT00702403"
        }
      ],
      "source_url": "https://www.ebi.ac.uk/chembl/api/data/drug_indication/117423.json"
    },
    {
      "drugind_id": 117424,
      "efo_id": "MONDO:0000873",
      "efo_term": "lymphoblastic lymphoma",
      "license": "CC BY-SA 3.0",
      "max_phase_for_ind": 4,
      "mesh_heading": "Precursor Cell Lymphoblastic Leukemia-Lymphoma",
      "mesh_id": "D054198",
      "molecule_chembl_id": "CHEMBL1642",
      "parent_molecule_chembl_id": "CHEMBL941",
      "references": [
        {
          "id": "NCT03023046",
          "type": "ClinicalTrials",
          "url": "https://clinicaltrials.gov/search?term=NCT03023046"
        }
      ],
      "source_url": "https://www.ebi.ac.uk/chembl/api/data/drug_indication/117424.json"
    }
  ],
  "min_phase": null,
  "molecule_chembl_id": "CHEMBL941",
  "next_cursor": "5",
  "observed_at_ms": 1792445177264,
  "offset": 0,
  "parent_molecule_chembl_id": "CHEMBL941",
  "pref_name": "IMATINIB",
  "total_count": 134
}

Browse the library

ChEMBL

Try ChEMBL now.

Related providers